A case of imported infection in China: Initially treatment-unresponsive schistosomiasis coinfection with bladder tuberculosis

作者：Langkun Wang, Lang Bai, Huan Li, Peng Zhang, Fang He · 发表于：Indian Journal of Medical Microbiology · 年份：2026 · DOI：10.1016/j.ijmmb.2026.101157 · 研究领域：Parasites and Host Interactions、Diagnosis and treatment of tuberculosis、Global Health and Epidemiology

Schistosoma haematobium, endemic to sub-Saharan Africa, causes urogenital disease, differing from Schistosoma japonicum, which affects the hepatointestinal system and is the only endemic schistosome in China. A Chinese male with persistent hematuria after prolonged occupational exposure in Angola was initially attributed to S. japonicum. Following failed treatment, metagenomic sequencing confirmed S. haematobium infection, and subsequent urethral resection detected Mycobacterium tuberculosis DNA, establishing concurrent bladder tuberculosis. This case highlights the need for molecular diagnostics in patients with hematuria after sub-Saharan exposure and the immunomodulatory risks posed by helminth infections.