Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair (Adv. Sci. 26/2026)

作者：Guanglin Niu, Jennifer Geara, Yongjian Chen, Lihua Luo, Yanwei Xiao, Zhuang Liu, Marion Gaborieau, Ling Pan, Edmund Loh, Dongqing Li, Pehr Sommar, Aoxue Wang, Xiaowei Zheng, Ning Xu Landén · 发表于：Advanced Science · 年份：2026 · DOI：10.1002/advs.75311 · 研究领域：Circular RNAs in diseases、GDF15 and Related Biomarkers、Cancer-related molecular mechanisms research

CircMT-RNR2-Mediated Wound Healing The cover illustrates mitochondrial CircMT-RNR2 RNA as a radiant golden ring binding to the PRDX3 protein, protecting fibroblasts from oxidative stress and enhancing their antioxidant defense and regenerative capacity. The background transitions from orange, representing chronic diabetic wounds, to blue as healing progresses, symbolizing CircMT-RNR2-mediated restoration of impaired wound repair. More details can be found in the Research Article by Guanglin Niu, Jennifer Geara, Ning Xu Landén, and co-workers (DOI: 10.1002/advs.202517141).