Hydrogel–exosome synergistic system: mechanisms, applications and future prospects in regenerative medicine

作者：Bin Xie, Yuyi Kang, Shuihao Zhao, Zhiyun Wu, Zelin Wu, Xiubin Kuang, Jiahong Jiang, Nuo Xu, Xudong Lin, Jun Wu, Tak Man Wong, Shaoquan Bian, Xiaoli Zhao, Zhengqiang Yuan · 发表于：Biomaterials Science · 年份：2026 · DOI：10.1039/d6bm00274a · 被引用次数：1 · 研究领域：Extracellular vesicles in disease、3D Printing in Biomedical Research、Hydrogels: synthesis, properties, applications

, pH, temperature) to control exosome release, optimizing the therapeutic efficacy. Additionally, exosome engineering for enhanced cargo loading and targeting capabilities further advances precision regenerative medicine. This review explores the latest progress, challenges, and future directions in harnessing hydrogels and exosomes for recently developed regenerative medicine and therapeutic applications.