What Is the Utility of 7 Tesla MRI for Deep Brain Stimulation Surgery? A Scoping Review

作者：Bryony Ishihara, David Carmichael, Shaihan Malik, Thomas Barrick, Franklyn Howe, Erlick Pereira, Michael G Hart · 发表于：Stereotactic and Functional Neurosurgery · 年份：2026 · DOI：10.1159/000552022 · 研究领域：Neurological disorders and treatments、Parkinson's Disease Mechanisms and Treatments、Functional Brain Connectivity Studies

BACKGROUND: Effective deep brain stimulation (DBS) requires precise visualisation of the target on magnetic resonance imaging (MRI). However, on clinical 3 Tesla (T) MRI these targets are often imperfectly delineated, introducing potential error. Higher magnetic field strength, e.g., 7T MRI ought to improve visualisation via resolution or contrast. Our aim was to appraise current evidence for proposed improvements with 7T MRI for DBS implantation. Specifically, we wanted to consider evidence for improvements in target visualisation, the imaging sequences that can leverage improvements, and how better MRI quality translated into clinical outcomes. SUMMARY: A scoping review was performed across multiple databases (PubMed and EMBASE). Search criteria included the terms ("7 Tesla" OR "7T") AND ("deep brain stimulation" OR "thalamus" OR "basal ganglia" OR "globus pallidus" OR "zona incerta" OR "pedunculopontine" OR "subthalamic nucleus"). Studies were selected based on target visualisation, sequence appraisal, or clinical application. Quantitative data were extracted for meta-analysis. 66 papers were identified. Target visualisation was improved with better signal- and contrast-to-noise ratio compared to 1.5T or 3T MRI, while manual segmentations of the subthalamic nucleus at 7T showed high inter-rater reliability (Dice = 0.75, 10 studies). Gradient echo sequences and quantitative susceptibility mapping offered the best demarcation and tissue contrast of basal ganglia structures. ...