Nano-silver triggers apoptosis through the mitochondria-dependent pathway in the gills of common carp

作者：Qianqian Xiang, Yanping Wu, Peng Wang, Hui Yan, L Chen · 发表于：Environmental Science Processes & Impacts · 年份：2026 · DOI：10.1039/d5em00972c · 研究领域：Aquaculture disease management and microbiota、Cell death mechanisms and regulation、Nanoparticles: synthesis and applications

genes. These findings demonstrate that nano-silver likely induces ROS overproduction to activate the MAPK pathway, thereby triggering mitochondria-dependent apoptosis in carp gills. This study enriches the mechanistic understanding of nano-silver toxicity in fish and provides molecular evidence for the risk assessment of nano-silver in aquatic ecosystems.