Molecular epidemiological analysis of Vibrio parahaemolyticus in foodborne diseases in Liaoning province, 2023–2024

作者：Weijie Wang, Xiangyun Liu, Lianzheng Yu, Mingyan Zhang, Tongzhu Wei, Xue Li, Jinghong Ma, Taoran Zhao, Yue Zheng, Qingyuan Wang, Yan Wang, Wenli Diao · 发表于：Frontiers in Public Health · 年份：2026 · DOI：10.3389/fpubh.2026.1780398 · 被引用次数：1 · 研究领域：Vibrio bacteria research studies、Aquaculture disease management and microbiota、Salmonella and Campylobacter epidemiology

Introduction Vibrio parahaemolyticus (VP) is a major pathogen causing foodborne diseases, and Liaoning Province, a coastal region with high seafood consumption and production, faces a notable risk of VP-associated foodborne infections. Clarifying the molecular epidemiological characteristics of VP in this region is critical for targeted prevention and control of such diseases. This study aimed to investigate the molecular epidemiological features, virulence gene profiles, and antibiotic resistance gene distribution of VP isolated from foodborne disease cases in Liaoning Province during 2023-2024, providing precise data support for VP prevention and control. Methods Whole-genome sequencing (WGS) was performed on 261 clinical isolates of Vibrio parahaemolyticus collected in Liaoning province from 2023 to 2024. Multilocus sequence typing (MLST), virulence gene identification, and antibiotic resistance gene detection were conducted and combined with epidemiological surveillance data to analyze the association between genetic and epidemiological characteristics. Results A total of 10,413 foodborne disease cases were monitored during 2023–2024, with 261 isolates of Vibrio parahaemolyticus identifed (detection rate: 2.51%). The positive rate in 2024 (3.59%) was significantly higher than that in 2023 (1.27%, P < 0.05). Vibrio parahaemolyticus infections showed obvious seasonal characteristics, with the majority of cases occurring in July–September, with a peak in August, and c...