Acid Ceramidase Inhibition Disrupts Ceramide Homeostasis and Induces Mitochondrial Apoptosis in IDH1-Mutant Oligodendroglioma

作者：Mioara Larion, Helena Muley, Faris Zaibaq, Meili Zhang, Dionne Davis, Michael J. Kruhlak, Samarth Mathur, Adrian Lita, Hua Song, Wei Zhang, Zalman Wong, Taylor A. Harmon, Lumin Zhang, Chen Makranz, Aiguo Li, George Karadimov, Fengchao Lang, Christel Herold-Mende, Chunzhang Yang, Tyrone Dowdy · 发表于：Research Square · 年份：2026 · DOI：10.21203/rs.3.rs-9077389/v1 · 研究领域：Sphingolipid Metabolism and Signaling、Caveolin-1 and cellular processes、Pharmacological Receptor Mechanisms and Effects