Retrospective Assessment of Social Rejection Related to Atopic Dermatitis During Childhood and Adolescence: The Scars of Life—Eczema Study

作者：Bruno Halioua, J. Tan, Chaoying Gu, Thomas Luger, Julien Sénéschal, Roni P. Dodiuk‐Gad, Roberto Takaoka, Flávia Pretti Aslanian, Cita Rosita Sigit Prakoeswa, Ann’ Laure Demessant‐Flavigny, Caroline Le Floc’h, Nabil Kerrouche, Stéphanie Mérhand, Wendy Smith Begolka, África Luca de Tena Smith, Shulamit Burstein, Delphine Kérob, C. Taïeb, Charbel Skayem, Abraham Getachew Kelbore, Laurent Misery, Therdpong Tempark, Alexander Stratigos, Martin Steinhoff, Jonathan I. Silverberg · 发表于：International Journal of Dermatology · 年份：2026 · DOI：10.1111/ijd.70375 · 被引用次数：1 · 研究领域：Dermatology and Skin Diseases、Psoriasis: Treatment and Pathogenesis、Dermatological diseases and infestations

Atopic dermatitis (AD) is a chronic inflammatory skin disease that often begins early in life and is associated with a substantial psychosocial burden [1]. Previous studies have shown that AD negatively affects quality of life and social relationships during childhood and adolescence [2]. However, experiences of social rejection related to AD during these developmental periods remain insufficiently documented, particularly when assessed retrospectively. Participants were asked to recall experiences of social rejection that occurred during childhood and adolescence. The analyses, therefore, reflect perceived social experiences related to AD during earlier life stages as recalled in adulthood and do not represent prospectively collected pediatric data. This study is based on a retrospective assessment conducted within the Scars of Life—Eczema study, among adult respondents with a self-reported, physician-confirmed history of atopic dermatitis from 27 countries, recruited in 2024 through an online quota-based survey designed to obtain nationally representative samples of the general population. Adult respondents reporting a history of atopic dermatitis were included. Two subgroups were defined according to the age at which atopic dermatitis first appeared: childhood-onset AD before the age of 10 years (CHIL group, n = 6161) and adolescent-onset AD between 10 and 18 years (TEEN group, n = 9289). Social rejection was assessed as perceived social exclusion using items addressing ex...