Cancer CARE (Connected Access and Remote Expertise) Beyond Walls — Safety, Feasibility, and Patient Experience of Home-Based Chemotherapy

作者：Roxana Dronca, Jeremy Jones, Michael J. Maniaci, Dina Elantably, Gina L. Mazza, Hemant S. Murthy, Tufia C. Haddad, Lucia Nolan, Jennifer L. Hunze, Deborah Fischer, Chanice A. Obi, Alexis Jackson, Amanda Biddle, Sunnie M. Confiado, Nathan Smith, Loizos Michaelides, Alfredo Quiñones-Hinojosa, Jennifer L. Ridgeway, Bijan J. Borah, Ajani N. Dunn, Kent R. Thielen, Cheryl L. Willman · 发表于：NEJM Catalyst · 年份：2026 · DOI：10.1056/cat.25.0168 · 被引用次数：1 · 研究领域：Augmented Reality Applications、Biomedical and Engineering Education、Mobile Health and mHealth Applications

As patients live longer with cancer, traditional treatment models centered around hospitals and infusion centers increasingly burden patients, caregivers, and health care systems alike. These burdens are logistical, financial, and emotional, and they are especially profound for older adults and individuals in rural or underserved areas, who face added challenges in accessing centralized care. To address these growing inequities and systemic pressures, Mayo Clinic piloted an innovative model of home-based chemotherapy through its Cancer CARE (Connected Access and Remote Expertise) Beyond Walls program - CCBW. This program reimagines oncology care by integrating virtual oversight, remote patient monitoring (RPM), mobile health services, and a unified software platform connected to the electronic medical record. From April 1, 2023, to August 31, 2023, the CCBW pilot enrolled 10 patients who, collectively, received 93 intravenous chemotherapy infusions at home. Clinical safety was closely monitored through a virtual command center, with RPM data and mobile care teams enabling timely intervention when needed. Across the pilot, there were no infusion reactions or catheter-related infections, and the minor complications, including two cases of hypokalemia and two unrelated falls, were successfully managed within the home setting, avoiding emergency department visits or hospitalization. Feedback from seven patients underscored the acceptability and advantages of this home-based appro...