On the Structural Role of MgO and ZnO in Bioactive Metasilicate Glasses

作者：Henrik Bradtmüller, Przemysław Gołębiewski, Catalin Constantin Negrila, George E. Stan, Ryszard R. Buczynski, Hellmut Eckert, José M.F. Ferreira, Anuraag Gaddam · 发表于：Journal of the American Ceramic Society · 年份：2026 · DOI：10.1111/jace.70614 · 被引用次数：1 · 研究领域：Bone Tissue Engineering Materials、Glass properties and applications、Clay minerals and soil interactions

ABSTRACT Magnesium and zinc are important additives or substituents in melt‐quenched Na 2 O–CaO–SiO 2 –P 2 O 5 bioactive glasses, due to their beneficial influence on glass stability and processability. They modify the dissolution kinetics of these glasses and impart favorable biological properties and functions to them. For rational bioactive glass design, it is essential to understand the local environments and distributions of these ions. While diffraction studies suggest MgO and ZnO to be close‐to‐four‐coordinate in silicate glasses, their structural roles in the network are still under debate. Traditionally these oxides have been viewed as network modifiers, converting Si–O–Si linkages to anionic non‐bridging oxygen atoms, whose charges are compensated by the divalent cations. It has been suggested that MgO 4/2 | 2– or ZnO 4/2 | 2– network‐forming units (NFUs) may be present, forming Mg–O–Si or Zn–O–Si linkages. If such units are formed, they would attract modifier cations for charge compensation, which would in turn result in an increased degree of polymerization of the silicate species, the main network‐forming component. This study explores the roles of MgO and ZnO in bioactive glasses with approximate composition 50SiO 2 –(50– x )[MO,M’ 2 O]– x P 2 O 5 in mol% (2 ≤ x ≤ 6), where M = Ca, Sr, Mg, Zn; M’ = Na, K. Quantitative estimates of the various silicate and phosphate NFUs were obtained from 29 Si and 31 P solid‐state nuclear magnetic resonance (NMR) spectroscopic ...