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Supplementary Data S3 from DNMT3A R882H Is Not Required for Disease Maintenance in Primary Human AML but Is Associated with Increased Leukemia Stem Cell Frequency

作者:Thomas Köhnke, Daiki Karigane, Eleanor Hilgart, Amy C. Fan, Kensuke Kayamori, Masashi Miyauchi, Cailin Collins, Fabian P. Suchy, Athreya Rangavajhula, Yang Feng, Yusuke Nakauchi, Eduardo Martínez‐Montes, Jonas L. Fowler, Kyle M. Loh, Hiromitsu Nakauchi, Michael A. Koldobskiy, Andrew P. Feinberg, Ravindra Majeti · 年份:2026 · DOI:10.1158/2159-8290.31443674 · 研究领域:Acute Myeloid Leukemia Research、Acute Lymphoblastic Leukemia research、Chronic Myeloid Leukemia Treatments

<p>Plots of top 100 DMRs (by area statistic & FWER) between DNMT3AR882H/WT re-mutated and DNMT3AWT/WT samples for patient SU575</p>