Effects of cochlear implantation on quality of life in patients with age-related hearing loss: a systematic review

作者：Xiangke Wang, Hongxia Lan, Ruilin Li, Zhanhang Zheng, Chenxingzi Wu, Shuhong Qin, Wenjuan Wang, Ting Chen · 发表于：Frontiers in Neuroscience · 年份：2026 · DOI：10.3389/fnins.2026.1778985 · 被引用次数：2 · 研究领域：Hearing Loss and Rehabilitation、Hearing, Cochlea, Tinnitus, Genetics、Hearing Impairment and Communication

Background: Age-related hearing loss (ARHL) is among the most prevalent sensory impairments in older adults. However, the magnitude and time course of quality-of-life (QoL) gains associated with cochlear implantation (CI) in ARHL, as well as potential differences across older age strata, have not been synthesized systematically. We conducted a systematic review to characterize QoL changes after CI in ARHL and to contrast the responsiveness of hearing/CI-specific instruments with that of generic QoL measures. Methods: Following PRISMA, we searched PubMed, Web of Science, Embase, the Cochrane Library, and CNKI from inception to 7 December 2025. Eligible studies enrolled adults aged ≥60 years meeting an ARHL definition, receiving CI, and reporting outcomes from validated QoL instruments. Two reviewers independently performed study selection and data extraction. Risk of bias in non-randomized studies was assessed using the ROBINS-I tool. Outcomes measured by different types of QoL instruments at each follow-up time point were synthesized narratively. Results: We included 16 studies (842 participants). According to ROBINS-I, most studies had at least moderate risk of bias, and approximately one third were judged to have a serious risk of bias. Across studies, hearing/CI-specific measures (e.g., Nijmegen Cochlear Implant Questionnaire, NCIQ and Glasgow Benefit Inventory, GBI) more consistently detected post-CI gains, particularly in domains related to sound perception and social su...