Progressive Bilateral Alterations in Gait Biomechanics Within 2 Years After Anterior Cruciate Ligament Reconstruction

作者：Yiqun Lu, Zhengye Ma, Mengting Zhang, Hua Zhang, Hongjie Huang, Hongjie Huang, Si Zhang, Xin Miao, Yuanyuan Yu, Jianing Wang, Hongshi Huang, Hongshi Huang, Shuang Ren · 发表于：Orthopaedic Journal of Sports Medicine · 年份：2026 · DOI：10.1177/23259671251386457 · 被引用次数：1 · 研究领域：Knee injuries and reconstruction techniques、Total Knee Arthroplasty Outcomes、Lower Extremity Biomechanics and Pathologies

Background: Bilateral gait biomechanics change over time after anterior cruciate ligament reconstruction (ACLR) and have been suggested to contribute to the development of osteoarthritis. However, few studies have investigated the longitudinal changes in bilateral gait biomechanics in the same cohort within 24 months after ACLR. Purpose: To evaluate the longitudinal changes in bilateral gait biomechanics compared with the healthy control cohort within 24 months after ACLR. Study Design: Controlled laboratory study. Methods: A total of 24 patients who underwent primary unilateral ACLR surgery with autologous hamstring tendon grafts and 24 matched healthy participants were included. Also, 3-dimensional knee gait and ground-reaction forces (GRF) information were collected at 3, 6, 12, and 24 months after ACLR. Linear mixed-effects models were used to assess the influence of time and limb in ACLR participants and their interaction effect on each variable of interest. Two-way analysis of variance was used to compare intergroup and interleg dependent variables. Results: Three months after ACLR, most biomechanical parameters of the operated limb (peak knee extension angle [pKEA]; peak knee extension moment [pKEM]; peak knee flexion moment [pKFM]; and vertical ground-reaction force [vGRF]) were lower than both the contralateral limb and healthy controls, and gradually increased over time. By 24 months postoperation, the pKEA and the pKEM returned to normal levels. The operated limb s...