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Risk factors for postpartum depression after cesarean section: a systematic review and meta-analysis

作者:Yali Yu, Hui Feng, Ma Peng · 发表于:PeerJ · 年份:2026 · DOI:10.7717/peerj.20550 · 被引用次数:3 · 研究领域:Maternal Mental Health During Pregnancy and Postpartum、Maternal and Perinatal Health Interventions、Mental Health Treatment and Access

Background The incidence of cesarean section (CS) is increasing each year and may be associated with an increased risk of postpartum depression (PPD). Although studies have examined the association between cesarean delivery and postpartum depression, the associated risk factors have not been fully investigated. This study aims to identify key risk factors for planned and emergency cesarean delivery through meta-analysis to help develop clinical prevention strategies. Methods We searched multiple databases, including CNKI, Wan Fang, VIP, PubMed, Embase, Scopus, Google Scholar, CINAHL, Cochrane Library, and Web of Science, for studies published from the inception of these databases through January 8, 2025. The quality of the studies was assessed using the Newcastle-Ottawa Scale (NOS), and standardized mean difference (SMD) and ratio of ratios (OR) were used to assess the strength of association between different risk factors and postpartum depression, when I 2 > 50%, a random effects model was used for data analysis; when I 2 < 50%, a fixed effects model was chosen for analysis. Result Nine articles ( n = 3,338) were included in this study, meta-analysis results suggest that younger women (SMD = −0.16, 95% CI [−0.29 to −0.04], I 2 = 0%), higher antenatal depression scores (SMD = 0.28, 95% CI [0.13–0.44], I 2 = 15.1%), higher antenatal anxiety scores (SMD = 0.56, 95% CI [0.40–0.72], I 2 = 35.6%) are more likely to experience postpartum depression, nulliparous (OR = 1.9, 95...