Vigorous intermittent lifestyle physical activity (VILPA) and mortality risk among US adults: a wearables-based national cohort study

作者：Nicholas A. Koemel, Matthew N. Ahmadi, Raaj Kishore Biswas, Cecilie Thøgersen-Ntoumani, Armando Teixeira-Pinto, C. Chow, Jaroslaw Harezlak, Emmanuel Stamatakis · 发表于：International Journal of Behavioral Nutrition and Physical Activity · 年份：2026 · DOI：10.1186/s12966-026-01876-2 · 被引用次数：4 · 研究领域：Physical Activity and Health、Cardiovascular and exercise physiology、Obesity, Physical Activity, Diet

BACKGROUND: Vigorous intermittent lifestyle physical activity (VILPA) completed through normal daily living may offer a time-efficient avenue to accrue physical activity in a behaviourally sustainable manner. However, no research to date has explored its association with mortality in a nationally representative population. This study aimed to examine the dose-response association between VILPA and mortality risk in a nationally representative sample of US adults. METHODS: This study included a nationally representative sample of 3293 US adults from the 2011-14 National Health and Nutrition Examination Survey (NHANES) who self-reported no participation in structured exercise (52.3% female; mean age: 50.7 [SD: 16.6 years]. The dose-response relationship between VILPA and all-cause mortality was estimated using multivariable-adjusted cubic splines. Average daily frequency (bouts/day) and duration (minutes/day) of VILPA bouts lasting up to one minute were measured using a wrist-worn accelerometer. RESULTS: Over the mean (SD) 6.7 (1.4) year follow-up period, 290 all-cause mortality events occurred. Compared to the referent point (0 bouts per day), there was an L-shaped dose-response association where the median frequency (5.3 bouts per day) was associated with a 44% lower risk of all-cause mortality (HR: 0.56; 95% CI: 0.39, 0.82). The dose response curve was less steep beyond approximately 8 bouts per day (HR: 0.46; 95% CI: 0.28, 0.77). Findings for the median frequency of VILPA b...