Electrophotochemical Anti-Markovnikov Selective Carboxylation of Alkenes

作者：Xinya Lv, Chunlei Liu, Li Liu, Y. Huang, Yuan Xu, Zhaoliang Yang, Jianye Zhang · 发表于：The Journal of Organic Chemistry · 年份：2026 · DOI：10.1021/acs.joc.5c02850 · 被引用次数：1 · 研究领域：CO2 Reduction Techniques and Catalysts、Carbon dioxide utilization in catalysis、Radical Photochemical Reactions

Carbon dioxide (CO 2 ), as an ideal single-carbon source in chemical synthesis, has garnered extensive attention for its direct utilization. The direct conversion of CO 2 via electrochemistry, an environmentally benign strategy, offers a crucial direction and immense potential for resource transformation in the context of carbon neutrality goals. However, due to the extremely low reduction potential of CO 2 itself, the electrochemical carboxylation process often inevitably leads to the formation of multiple products, resulting in poor reaction selectivity. To tackle this challenge, a photoelectrochemical strategy is reported for the efficient reduction of CO 2 and the anti-Markovnikov selective carboxylation of activated and unactivated alkenes. The reaction is simple to perform, requiring no additional chemical oxidants throughout the process. Experimental verification confirms that it exhibits excellent applicability to a wide range of alkene substrates, thereby providing a new pathway for highly selective and green carboxylation synthesis.