Multiparatopic antibodies overcome tyrosine kinase inhibitor resistance by inducing lysosomal degradation of EGFR mutants

作者：Deli Huang, Yaoji Liang, Chunjie Lin, Jie Liu, Jiacheng Ni, Dingrui Chen, Yafei Liu, Wanyinhui Zhu, Yinuo Sheng, Yunling Wang, Yingbin Gao, Sitong Zhang, Weirui Ma · 发表于：Research Square · 年份：2026 · DOI：10.21203/rs.3.rs-8437918/v1 · 研究领域：Monoclonal and Polyclonal Antibodies Research、HER2/EGFR in Cancer Research、Lung Cancer Treatments and Mutations