Transcriptomics and functional genomics implicate WNT3 in hemispheric lateralization of speech production

作者：Zixian Wang, Yanxi Chen, Yongqi Feng, Gaoyu Zu, Wenxu Wang, Limiao Liang, Xinyu Liu, Yuhang Mei, Jiaxuan Yang, Tian Wang, Mengqi Liu, Linxi Jiang, Russell G. Snell, Blake Highet, Maurice A. Curtis, Liang Chen, Shi-Bin Li, Jinsong Wu, Menghan Zhang, Wensheng Li, Gong‐Hong Wei, Linya You · 发表于：iScience · 年份：2026 · DOI：10.1016/j.isci.2026.114692 · 被引用次数：1 · 研究领域：Hemispheric Asymmetry in Neuroscience、Stress Responses and Cortisol、Transcranial Magnetic Stimulation Studies

OE) in the dorsal striatum selectively altered ultrasonic vocalizations (USVs), locomotor activity, and myelin basic protein expression. These results connect regulatory variation to lateralized gene control and circuit function relevant to vocal communication, and provide a multiregional resource to support mechanistic studies in human tissue and animal models.