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Case of Advanced Hepatocellular Carcinoma Treated With Transarterial Radioembolization and Subsequent Liver Transplantation in a 22-Month-old

作者:Frances Hanson, Brian T Hickner, Carleigh C. Fisher, Hailey Hein, Kamlesh Kukreja, John Goss, Thao N. Galvan, Daniel H. Leung, Anna M. Banc-Husu, Prakash Masand, Kalyani R. Patel, Dolores López‐Terrada, Andras Heczey, Sanjeev Vasudevan, Julie Voeller · 发表于:Journal of Pediatric Hematology/Oncology · 年份:2025 · DOI:10.1097/mph.0000000000003152 · 被引用次数:1 · 研究领域:Hepatocellular Carcinoma Treatment and Prognosis、Organ Transplantation Techniques and Outcomes、Cholangiocarcinoma and Gallbladder Cancer Studies

Hepatocellular carcinoma (HCC) is a rare malignancy in children, typically requiring chemotherapy, surgical resection, and/or transplant for treatment. Whether HCC arises as a novel tumor (de novo) or in the setting of chronic liver disease determines treatment strategy. We describe a case of a pediatric patient with unresectable HCC due to macrovascular invasion and tumor thrombus of the portal vein who received transarterial radioembolization (TARE) and underwent successful orthotopic liver transplantation outside of Milan criteria.