TOTAL ACID-BASE EQUILIBRIUM OF PLASMA IN HEALTH AND DISEASE

作者：John Punnett Peters, A. Maurice Wakeman, Anna J. Eisenman, Carter Lee · 发表于：Journal of Clinical Investigation · 年份：1929 · DOI：10.1172/jci100210 · 被引用次数：53 · 研究领域：Redox biology and oxidative stress

Since the earlier papers Van Slyke and his associates (5) have established more accurately the base combining powers of the total proteins of human serum and the albumin and globulin fractions respectively.The equation originally used for converting protein concentrations to equivalents of base combined with protein derived from data published by Van Slyke, Wu and McLean (4) from the blood of a Manchurian pony, was: BP = 0.68 P (pH-4.8)The new equations are: for albumin BP(alb.)= 1.248P(alb.)(pH -5.16) for globulin BP(glob.)= 0.742 P(glob.)(pH -4.82)TABLE 2 Proten concentration in normal serum Calculated Subject sex Age Albumin Globulin Total protein A: G total protein percen r.n-eq.percent m.-eq.percent m.-eq.ratio rm-eq.if A:G -1.2 A.:E. Female 28 5.21 14.2 3.00 5.6 8.21 19.9 1.74 20.3 H. 0. Male 27 5.31 14.5 1.32 2.5 6.63 17.0 4.02 16.4 5.49 15.0 1.95 3.6 7.44 18.6 2.82 18.4 F. B. Male 29 5.65 15.4 1.58 3.0 7.23 18.4 3.58 17.9 E. D. Male 26 5.37 14.7 1.95 3.6 7.32 18.3 2.75 18.1 H. D. Female 15 55.17 14.1 3.22 6.0 8.39 20.1 1.61 20.8 M. W. Male 5.29 14.5 2.31 4.3 7.60 18.8 2.25 18.8 H. Male 5.31 14.5 2.11 4.0 7.42 18.5 2.52 18.4 R. I. Female 31 4.83 13.2 2.39 4.5 7.22 17.7 2.02 17.9 F. Female 4.98 13.6 2.44 4.6 7.42 18.2 2.04 18.4 R. Male 4.74 13.0 2.91 5.4, 7.65 18.4 1.63 18.9 J. P. Male 40 4.69 12.8 1.84 3.4 6.53 16.2 2.55 16.2 D. M. Male 29 5.20 14.2 1.59 3.0 6.79 17.2 3.27 16.8 5.24 14.3 1.61 3.0 6.85 17.3 3.26 17 .05.19 14.2 1.90 3.6 7.09 17.8 2.73 17.5 5.49 15.0 1.51...