A countrywide study on post-COVID-19 condition in Brazil: the Epicovid 2.0

作者：Fernando C. Wehrmeister, Ana Maria Baptista Menezes, Margareth Pretti Dalcolmo, Elena de Carvalho Cremm, Talita S. B. Batista, Otávio Amaral de Andrade Leão, Cauane Blumenberg, Fernando Vinholes Siqueira, Cláudio J. Struchiner, César G. Victora, Pedro Curi Hallal · 发表于：International Journal of Epidemiology · 年份：2025 · DOI：10.1093/ije/dyaf143 · 被引用次数：2 · 研究领域：Long-Term Effects of COVID-19、SARS-CoV-2 and COVID-19 Research、COVID-19 Clinical Research Studies

BACKGROUND: The COVID-19 pandemic had severe impacts worldwide. We assessed the occurrence of a post-COVID-19 condition (PCC) in Brazil and described the persistence of symptoms 4 years after the start of the pandemic. METHODS: A population-based survey was carried out in 133 large cities in 2024. The current prevalence of 21 COVID-19-related symptoms was recorded for all respondents, regardless of infection history. The World Health Organization's definition of PCC was adopted. Results were described by country region and socio-demographic characteristics. RESULTS: Of the 33 250 individuals sampled, 28.6% [95% confidence interval (CI) 27.3 to 30.0] reported having had COVID-19, of whom 65.1% (95% CI 62.7 to 67.4) fulfilled the criteria for PCC at any time in the past. Prevalence of PCC was highest among those who were hospitalized and needed intubation or oxygen support [85.3% (95% CI 79.6 to 89.7)]. The average number of current symptoms among those with PCC was 7.21 (95% CI 6.73 to 7.69) compared with 2.77 (95% CI 2.62 to 2.92) among those without a COVID-19 history. The most common symptoms for those with COVID-19 history were memory loss, anosmia, loss of sensitivity in the hands, difficulty in concentration, and hair loss. Women and Indigenous individuals presented a higher average number of symptoms compared with those without a history. CONCLUSION: A high proportion of individuals who suffered from COVID-19 presented symptoms 4 years after the SARS-CoV-2 emergence; al...