Streptomyces yinggelingensis sp. nov. YGL11-2: A novel biocontrol agent with dual activity against banana soil-borne and postharvest fungal diseases

作者：Chunting Li, Xiaohong Ou, Dengfeng Qi, Wei Wang, Guopeng Zhu, Yufeng Chen, Miaoyi Zhang, Yankun Zhao, Yongzan Wei, Junting Feng, Kai Li, Dengbo Zhou, Jianghui Xie · 发表于：Biological Control · 年份：2025 · DOI：10.1016/j.biocontrol.2025.105947 · 被引用次数：3 · 研究领域：Plant-Microbe Interactions and Immunity、Microbial Natural Products and Biosynthesis、Genomics and Phylogenetic Studies

Banana production is severely threatened by both Fusarium wilt (caused by Fusarium oxysporum f. sp. cubense tropical race 4, Foc TR4) and anthracnose (caused by Colletotrichum musae ), which are devastating soil-borne and postharvest diseases, respectively. Biocontrol using antagonistic microorganisms offers an eco-friendly alternative for managing the concurrent occurrence of soil-borne and postharvest pathogens. In this study, strain YGL11-2 was isolated and characterized as a novel species of Streptomyces through polyphasic taxonomy, for which we propose the name Streptomyces yinggelingensis sp . nov . Genomic analysis of this strain revealed 48 secondary metabolite gene clusters, including compounds such as Ectoine and Anantin C, which exhibit potential antifungal activity. Strain YGL11-2 demonstrated dual antagonistic activity against Foc TR4 and C. musae , with half-maximal effective concentrations (EC 50 ) values of 12.01 mg/L and 25.31 mg/L, respectively. Regarding antifungal mechanisms, strain YGL11-2 extracts disrupted fungal cell membrane structures, caused hyphal and spore wrinkling and breakage, and inhibited spore germination. Pot experiments confirmed that banana seedlings treated with strain YGL11-2 extracts showed a reduced Foc TR4 disease index, achieving a control efficacy of 41.94 %, while significantly promoting root growth (+10.55 cm) and biomass accumulation (+46.40 %). In fruit experiments, bananas treated with strain YGL11-2 exhibited an anthracnose i...