National and subnational burden and causes of anemia in China from 1990 to 2023: findings from the Global Burden of Disease Study 2023

作者：Zheng Long, Lingling Yu, Fanshu Yan, Peipei Li, Lijun Wang, Maigeng Zhou, Bingxin Ji, Peng Yin · 发表于：Military Medical Research · 年份：2025 · DOI：10.1186/s40779-025-00681-5 · 被引用次数：3 · 研究领域：Iron Metabolism and Disorders、Erythropoietin and Anemia Treatment、Folate and B Vitamins Research

BACKGROUND: Anemia is a major global health problem. There were 89% of all anemia-related disabilities in developing countries. We aim to analyze the burden of anemia and its underlying causes in China from 1990 to 2023. METHODS: Utilizing the data of the 2023 Global Burden of Disease (GBD 2023) study, this study analyzed the burden of anemia in China between 1990 and 2023. Then we analyzed the number and rate of anemia attributed to 16 underlying causes for all genders and ages. Drivers of change in prevalence and years lived with disability (YLD) numbers due to anemia were explored by decomposition analysis. And locally weighted regression was used to estimate the relationship between socio-demographic index (SDI) and age-standardized prevalence rate (ASPR) and age-standardized YLD rate due to anemia. RESULTS: From 1990 to 2023, the ASPR and age-standardized YLD rate showed a downward trend among all anemia types (P < 0.05), and the ASPR and age-standardized YLD rate of anemia in females were higher than those in males. The highest number and rate of prevalence were found in mild anemia, and the highest number and rate of YLD were found in moderate anemia. As age increased, the prevalence and YLD rate of anemia increased, with a significant increase in females aged 20-54, in particular of moderate anemia. In 2023, the highest ASPR and age-standardized YLD rate among all anemia types were in the Northwestern regions. Compared to 1990, 31 provinces, Hong Kong, and Macao exhib...