An assessment of intrinsic capacity among older Indian adults from the Longitudinal Ageing Study in India

作者：Arokiasamy Perianayagam, Ritu Sadana, Matthew Prina, Y. Selvamani, Aravinda Meera Guntupalli, David E. Bloom, Jinkook Lee, Yu-Tzu Wu · 发表于：Nature Aging · 年份：2025 · DOI：10.1038/s43587-025-01013-x · 被引用次数：2 · 研究领域：Balance, Gait, and Falls Prevention、Frailty in Older Adults、Dementia and Cognitive Impairment Research

Intrinsic capacity (IC), which comprises all physical and mental capacities of individuals, is a key component in the World Health Organization’s healthy aging framework. A validated IC measure is lacking in India, the most populous country in the world. The aim of this study is to develop an IC measure in older Indian adults using 60,591 participants aged ≥45 years from the Longitudinal Ageing Study in India. Confirmatory factor analysis incorporated 14 items of cognitive, locomotor, psychological, sensory and vitality capacities in a bifactor structure and estimated IC scores (range 0–100). The mean score was 69.7 (95% confidence interval of 69.6 to 69.8) and varied across the 36 states and union territories (range 63.4–77.8). A higher IC score had protective associations with poor self-rated health and functioning limitations after adjusting for demographic factors, socioeconomic status and chronic conditions. The score provides a comprehensive indicator that can be implemented in future aging research and practices in India. Intrinsic capacity (IC) was introduced by the World Health Organization to promote healthy aging. Here, using data from the Longitudinal Ageing Study in India, the authors develop an IC measure for older Indian adults. Their analysis shows that higher IC scores are associated with better health and functioning and reveals regional and sociodemographic variations.