Programmatic approaches to screening for tuberculosis disease: a situational analysis of seven countries in the Western Pacific Region

作者：Alvin Kuo Jing Teo, Kyung Hyun Oh, Manami Yanagawa, Cecily Miller, Dennis Falzon, Avinash Kanchar, Youngeun Choi, Gyeong In Lee, Fukushi Morishita, Kalpeshsinh Rahevar, Rajendra Yadav, Huong Thi Giang Tran, Anousone Sisouvanh, Bunleng Bith, Clarissa Blanca, Ganpurev Byambaa, Herolyn Nindil, Huyen Thanh Truong, Janet Ibay, Kim Eam Khun, Narantuya Jadambaa, Quang Hieu Vu, Sakhone Suthepmany, Serongkea Deng, Uyanga Erdenebileg, Vibol Iem, Vilath Seevisay, Walley Ambano, Zhenhong Li, Zhongdan Chen · 发表于：Tropical Medicine and Health · 年份：2025 · DOI：10.1186/s41182-025-00846-x · 被引用次数：2 · 研究领域：Tuberculosis Research and Epidemiology、Diagnosis and treatment of tuberculosis、Healthcare Facilities Design and Sustainability

BACKGROUND: Tuberculosis (TB) remains a significant public health challenge in the Western Pacific Region, which accounts for approximately 20% of the global TB burden. Despite effective diagnostic tools and treatment, many individuals with TB remain undiagnosed or unreported, particularly in high-burden countries. Systematic screening is a key strategy for identifying cases early and reducing transmission. This study presents a situational analysis of TB screening policies, practices, and challenges across seven high-burden countries in the region: Cambodia, China, Lao PDR, Mongolia, Papua New Guinea, the Philippines, and Viet Nam. MAIN BODY: Data were collected through questionnaires, follow-up discussions, and a regional workshop involving National TB Programme representatives and WHO staff. Most countries have national guidelines for systematic screening, prioritising high-risk groups, like people living with HIV and household contacts. Common screening tools include symptom screening, chest X-rays, and WHO-recommended rapid molecular diagnostics. Although asymptomatic TB is increasingly recognised, symptom screening remains the primary initial tool. Chest X-rays with computer-aided detection technologies are available in most countries, but are often limited to donor-funded projects. Screening is conducted through routine healthcare visits, scheduled checks for specific populations (e.g., prisoners, older adults), and ad hoc campaigns. Implementation varies due to resour...