Visible-Light-Induced Difunctionalization of Alkenes with Thioacids and Quinoxalin-2(1 H )-ones

作者：Huanhuan Cui, Zhen Ma, Huilan Yue, Huirong Xia, Wei Wei, Zi Yang, Zuli Wang, Dong Yi · 发表于：The Journal of Organic Chemistry · 年份：2025 · DOI：10.1021/acs.joc.5c02640 · 被引用次数：16 · 研究领域：Radical Photochemical Reactions、Oxidative Organic Chemistry Reactions、Catalytic C–H Functionalization Methods

A visible-light-induced difunctionalization of alkenes with quinoxalin-2(1 H )-ones and thioacids has been developed at room temperature. The present protocol, which utilizes 4CzIPN as the photocatalyst and K 3 PO 4 as base, provides a series of structurally diverse thioester-containing quinoxalin-2(1 H )-ones in moderate to good yields. This transformation undergoes through a radical pathway with the simultaneous installation of thioester and quinoxalin-2(1 H )-one into one structural framework.