Patient engagement and shared decision-making in trial recruitment intervention studies: a systematic review

作者：Tamara L. Morgan, Natasha Hudek, Kelly Carroll, Mei-Lin Yee, Juliette Inglis, Dean Fergusson, Katie Gillies, Dawn P. Richards, Seana N. Semchishen, Justin Presseau, Jeremy Grimshaw, Ian D. Graham, Marc Rodger, Monica Taljaard, Susan Marlin, Charles Weijer, Graeme MacLennan, Jamie C. Brehaut · 发表于：Research Involvement and Engagement · 年份：2025 · DOI：10.1186/s40900-025-00806-z · 被引用次数：1 · 研究领域：Mental Health and Patient Involvement、Ethics in Clinical Research、Patient-Provider Communication in Healthcare

Supporting participation decisions and experiences in clinical trials is a persistent challenge that could be improved by two areas: patient engagement (PE), which involves actively collaborating with patients to enhance research relevance and value, and shared decision-making (SDM), which involves helping individuals make evidence-informed, values-based decisions about participation. The extent to which PE and SDM have informed trial recruitment interventions has not been synthesized. We aimed to explore (1) how PE informed recruitment interventions, both in general and among equity-deserving populations, and whether demographic differences existed between studies using and not using PE, and (2) how SDM has informed recruitment interventions, both in general and among equity-deserving populations. We identified randomized and quasi-randomized recruitment intervention studies from a prior Cochrane review and the Online Resource for Research in Clinical triAls database. We assessed recruitment interventions for reporting of PE and coded the level at which PE occurred (‘substantive engagement’, ‘limited engagement’, ‘both’, ‘unclear’, or ‘no engagement’) and the areas in which PE occurred (development of the research question, intervention design, selecting outcomes, dissemination/implementation, or ‘other’). We coded SDM across six domains: providing information about options, probabilities, clarifying outcomes, guidance in deliberation, using evidence, and disclosure and tran...