Prevalence and Factors Associated with Sarcopenia in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis

作者：Leixia Wang, Jianqian Chao, Na Zhang, Xinyue Li, Jianxia Li, Shengxuan Jin, Gangrui Tan, Tong Chen, Yibo Wu · 发表于：Gerontology · 年份：2025 · DOI：10.1159/000549808 · 被引用次数：21 · 研究领域：Nutrition and Health in Aging、Frailty in Older Adults、Body Composition Measurement Techniques

Introduction: Sarcopenia is a growing concern as a geriatric syndrome associated with various adverse health outcomes. Determining its prevalence and identifying risk factors are essential for effective prevention. This systematic review and meta-analysis aimed to estimate the prevalence of sarcopenia and identify the factors associated with sarcopenia in community-dwelling older adults. METHODS: Guided by the PICo framework, we systematically searched six databases for relevant literature. Two reviewers independently assessed the quality of included studies. We performed a meta-analysis to estimate the prevalence of sarcopenia in overall older adults and subgroups. For risk factor analysis, pooled odds ratios (ORs) with 95% CIs were calculated, employing either random or fixed-effects models as appropriate. RESULTS: A total of 52 eligible studies involving 70,202 older adults were included, among whom 7,488 were male and 9,054 were female. Forty studies were analyzed for both prevalence and related factors, while the remaining 12 were used for prevalence estimation only. The pooled analysis revealed a wide variation in the prevalence of sarcopenia among community-dwelling older adults, ranging from 5.2% to 50.0%, with an overall estimated prevalence of 18.8% (95% CI: 15.6%-22.4%) and substantial heterogeneity (I2 = 99.3%). Subgroup analyses showed that the highest rates were identified in studies using the EWGSOP 2018 definition (25.8%), Europe populations (23.4%), and using...