Research progress on ionic liquid-functionalized magnetic Fe3O4 nanomaterials in sample pretreatment- chromatographic analysis

作者：Jiaxin Li, Lizhu Zhao, X. Sun, Z. Y. He, Hui Cao, Yingjin LUO, Bo Yang · 发表于：Chinese Journal of Chromatography · 年份：2025 · 被引用次数：2 · 研究领域：Ionic liquids properties and applications、Analytical chemistry methods development、Extraction and Separation Processes

The analysis of complex sample matrices， such as environmental samples， food commodities， and biological specimens， requires sophisticated pretreatment methods. These techniques are fundamentally critical for isolating and enriching analytes of interest， thereby substantially enhancing the sensitivity， accuracy， and efficiency of subsequent analytical procedures. The judicious selection of adsorbent materials represents the pivotal element in achieving effective pretreatment. In recent years， ionic liquid-functionalized magnetic Fe3O4 nanoparticles （IL-Fe3O4 NPs） have garnered significant attention as highly promising materials within this domain. Their potential arises from an exceptional combination of properties： outstanding chemical and colloidal stability， high adsorption capacity， abundant surface active sites， superior solvation capabilities for diverse organic and inorganic compounds， potential for regeneration and reuse， and facile magnetic separation facilitated by an external magnetic field. Ionic liquids （ILs） are characterized by their structurally tailorable nature， excellent ionic conductivity， and potent dissolution capabilities. These intrinsic attributes render ILs highly effective as modifiers for Fe3O4 nanoparticles， either applied singularly or in hybrid composites with other functional materials. This surface functionalization fulfills two essential roles： firstly， it effectively mitigates the inherent tendency of nanoparticles towards agglomeration and ...