TMT1A inhibits lung adenocarcinoma progression by suppressing M2 macrophage polarization

作者：Junfan Pan, Qiongwen Wu, Yunan Zhao, Sixuan Wu, He Liu, Qihong Pan, Xiaohui Chen, Jing Zhang, XU Yi-quan · 发表于：iScience · 年份：2025 · DOI：10.1016/j.isci.2025.114332 · 研究领域：Ferroptosis and cancer prognosis、Immune cells in cancer、Epigenetics and DNA Methylation

T cell infiltration in LUAD. These findings demonstrated tumor-suppressive functions coupled with its immunomodulatory capacity position TMT1A as a promising therapeutic target for LUAD treatment.