Basal level of ATF4 promotes T cell readiness for activation-induced proliferation

作者：Yaolin Yi, Ce Luo, Jingyi Wang, Yujia Wang, Lixue Jin, Xiuyuan Sun, Jie Hao, Guoping Deng, Rong Jin, Qing Ge · 发表于：iScience · 年份：2025 · DOI：10.1016/j.isci.2025.114277 · 被引用次数：2 · 研究领域：Endoplasmic Reticulum Stress and Disease、Mitochondrial Function and Pathology、PI3K/AKT/mTOR signaling in cancer

. Our findings suggest that a basal level of ATF4 during the early phase of T cell activation enhances the preparedness of cells to cope with integrated stresses during the activation course.