Allergic Rhinitis and Its Impact on Asthma ( ARIA )‐ EAACI Guidelines—2024–2025 Revision: Part I—Guidelines on Intranasal Treatments

作者：Bernardo Sousa‐Pinto, Jean Bousquet, Rafael José Vieira, Holger J. Schünemann, Torsten Zuberbier, Antonio Bognanni, Alkis Togias, Bolesław Samoliński, Arunas Valiulis, Sian Williams, Anna Bedbrook, Wienczyslawa Czarlewski, Marı́a José Torres, Mohamed H. Shamji, Mário Morais‐Almeida, Giorgio Walter Canonica, Leticia de las Vecillas, Mark S. Dykewicz, Cristina Jacomelli, Ludger Klimek, Lucas Leemann, Olga Lourenço, Yuliia Palamarchuk, Nikolaos G. Papadopoulos, Ana Margarida Pereira, Marine Savouré, Sanna Toppila‐Salmi, Maria Teresa Ventura, Juan José Yepes-Núñez, Álvaro A. Cruz, Giorgio Ciprandi, Bilun Gemicioğlu, Mattia Giovannini, Brigita Gradauskienė, Tuomas Jartti, Miloš Jeseňák, Piotr Kuna, Violeta Kvedarienė, Désirée Larenas‐Linnemann, Amir Hamzah Abdul Latiff, Yousser Mohammad, Ken Ohta, P A Mahesh, Isabella Pali‐Schöll, Oliver Pfaar, Frederico S. Regateiro, Nicolás Roche, Luís Taborda‐Barata, Charlotte Suppli Ulrik, Marylin Valentin Rostan, Giovanni Viegi, Luo Zhang, Tari Haahtela, Iván Chérrez-Ojeda, Juan Carlos Ivancevich, Nikolaï Khaltaev, Arzu Yorgancıoğlu, Baharudin Abdullah, Mona Al‐Ahmad, Maryam Al‐Nesf, Rita Amaral, Julijana Asllani, Karl‐Christian Bergmann, Jonathan A. Bernstein, Michael S. Blaiss, Fulvio Braido, Paulo Augusto Moreira Camargos, Pedro Martins, Thomas B. Casale, Lorenzo Cecchi, Alessandro Fiocchi, Antonio Francesco Maria Giuliano, George Christoff, Ieva Cirule, Jaime Correia de Sousa, Elı́sio Costa, Stefano R. Del Giacco, Philippe Devillier, Dejan Dokic, Elham Hossny, Tomohisa Iinuma, Carla Irani, Zhanat Ispayeva, Kaja Julge, Ігор Петрович Кайдашев, Kazi S. Bennoor, Helga Kraxner, Inger Kull, Marek Kulus, Maciej Kupczyk, А.И. Курченко, Stefania La Grutta, Neven Mičulinić, Lan Le Thi Tuyet, Μichael Μakris, Branislava Milenković, Sang Min Lee, Stephen Montefort, André Moreira, Joaquim Mullol, Rachel Nadif, Alla Nakonechna, Hugo Neffen, Marek Niedoszytko, Dieudonné T. Nyembue, Robyn E. O’Hehir, İsmail Öğülür, Yoshitaka Okamoto, Heidi Olze, Óscar Palomares, Petr Panzner, Vincenzo Patella, Ruby Pawankar, Constantinos Pitsios, Todor A. Popov, Francesca Puggioni, Santiago Quirce, Agnė Ramonaitė, Marysia Recto, María Susana Repka-Ramirez, Graham Roberts, Karla Robles‐Velasco, Menachem Rottem, Marianella Salapatas, J. Sastre, Nicola Scichilone, Juan‐Carlos Sisul, Dirceu Solé, Manuel E. Soto‐Martínez, Milan Sova, Pongsakorn Tantilipikorn, Ana Todo‐Bom, Vladyslav Tsaryk, Ioanna Tsiligianni, Marilyn Urrutia‐Pereira, Erkka Valovirta, Tuula Vasankari, Dana Wallace, De Yun Wang, Margitta Worm, Osman Yusuf, Mihaela Zidarn, Sara Gil‐Mata, Manuel Marques‐Cruz, Bassam Mahboub, Ignacio J. Ansotegui, Antonino Romano, Werner Aberer, Maria Cristina Artesani, Elena Azzolini, Bruno Acatauassú Paes Barreto, Joan Bartra, Sven Becker, Bianca Beghé, Attilio Boner, E Borowiack, Jacques Bouchard, M. Bourgoin‐Heck, Luisa Brussino, Roland Buhl, José Antonio Castillo Vizuete, D. Charpin, Niels H. Chavannes, Marta Chełmińska, Lei Cheng, Ekaterine Chkhartishvili, Seong Cho, Herberto José Chong‐Neto, Deepa Choudhury, Derek K. Chu, Cemal Cingi, Enrico Compalati, Raquel Costa, Olga Mariana Cunha, Biljana Cvetkovski, Victoria Cardona‐Dahl, Gennaro D’Amato, Janet M. Davies, Danilo Di Bona, Sandra Nora González Díaz, Maria Dimou, Maria Doulaptsi, Renato Ferreira‐da‐Silva, Radosław Gawlik, María Julia Calvo-Gil, Özlem Göksel, Maximiliano Gómez, Maia Gotua, Christos Grigoreas, Ineta Grisle, María Antonieta Guzmán, Rachel Tan, Michael E. Hyland, Despo Ierodiakonou, Aspasia Karavelia, Paul K. Keith, Marta Kisiel, Tanja Soklič Košak, Mitja Košnik, Ilgım Vardaloğlu, Vicky Kritikos, Justyna Lityńska, Carlo Lombardi, Gilles Louis, Matteo Martini, Cem Meço, Eris Mesonjësi, F Mihălţan, Marcin Moniuszko, Robert N. Naclerio, Kari C. Nadeau, Sophia Neisinger, Markus Ollert, Michał Ordak, Giovanni Paoletti, Hae‐Sim Park, Elena Parmelli, Edgar Arturo Perdomo‐Flores, José Miguel Fuentes Pérez, N. Pham‐Thi, Emmanuel Prokopakis, Inês Ribeiro‐Vaz, Giovanni Rolla, Jan Romantowski, Philippe Rombaux, Philip W. Rouadi, Maia Rukhadze, Dermot Ryan, Ewelina Sadowska, Daiju Sakurai, Laila Salameh, Faradiba Serpa Sarquis, Élie Serrano, Jane da Silva, Michael Soyka, Krzysztof Specjalski, Vesna Tomić-Spirić, Katarina Stevanovic, Abirami Subramaniam, Maria Do Céu Teixeira, Tuuli Thomander, Martina Vachová, Marianne van Hage, Pakit Vichyanond, Martin Wagenmann, Fanny W.S. Ko, Pascal Werminghaus, Paraskevi Xepapadaki, Yi‐Kui Xiang, Qintai Yang, Daniela Rivero‐Yeverino, Jaron Zuberbier, João Fonseca · 发表于：Allergy · 年份：2025 · DOI：10.1111/all.70131 · 被引用次数：30 · 研究领域：Allergic Rhinitis and Sensitization、Sinusitis and nasal conditions、Respiratory and Cough-Related Research

BACKGROUND: Allergic rhinitis (AR) impacts quality of life, work and school productivity. Over the last years, an important body of evidence resulting from mHealth data has led to a better understanding of AR. Such advances have motivated an EAACI-endorsed update of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines (ARIA 2024-2025). This manuscript presents the ARIA 2024-2025 recommendations for intranasal treatments, one of the mainstays for AR management. METHODS: The ARIA 2024-2025 guideline panel issued recommendations following the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) evidence-to-decision framework. Several sources of evidence were used to inform panel judgments and recommendations, including systematic reviews, evaluation of mHealth and pharmacovigilance data, as well as a survey of experts on costs. RESULTS: Eleven guideline questions concerning intranasal treatments for AR were prioritized, leading to recommendations. Overall, these questions concern the choice between different classes of intranasal medications-most notably, intranasal corticosteroids (INCS), antihistamines (INAH), fixed combinations of INAH+INCS and decongestants-or between different individual medications within each class. Four questions had not been evaluated in previous ARIA guidelines, while for the other three there was a change in the strength or directionality of recommendations. Overall, recommendations point to the suggested use of INAH...