Recommendations from the WHO guideline for the prevention, diagnosis, and treatment of infertility

作者：Adam Balen, Ben J Cohlen, Carin Huyser, Dmitry M. Kissin, Nalini Mahajan, Ragaa Mansour, Alfred Murage, Richard H. Reindollar, Roberta Rizzo, Rita Sembuya, Gamal I. Serour, Basil C. Tarlatzis, Carla Tatone, Marie Lena Windt De Beer, Cong Yali, David G. Adamson, Amal Benbella, Márcia Mendonça Carneiro, Julia Mato Chaín, Ivonne Jeannette Díaz Yamal, Bart C.J.M. Fauser, Muntaha Gharaibeh, Grigoris Grimbizis, Joyce Harper, Marcia C. Inhorn, Mohan S Kamath, Tamar Khomasuridze, Neena Malhotra, Edgar Mocanu, Ben Willem Mol, Olarik Musigavong, Zozo Nene, Robert J. Norman, Sasha Ottey, Ameet Patki, Jie Qiao, Promise E. Sefogah, Trịnh Thế Sơn, Oleg Tishkevich, Karla Torres, Sheryl van der Poel, Mónica H. Vazquez‐Levin, Maria P. Vélez, Nathalie Vermeulen, Mohamed Ahmed Youssef, Lianne Gonsalves, Ndema Habib, Aasa Nihlén, Nandita Thatte, Daniel McCartney, Remco P. H. Peters, Teodora Wi, Dongbo Fu, Kerstin Schotte, Elena Fidarova, Lorenzo Moja, Meera Thapa Upadhyay, Oleg Kuzmenko, Ian Askew, Rajat Khosla, Thabo Matsaseng, Paula Amato, Priya Satalkar-Götz, Jaime Onofre, Marion Blacker, Rebekah Thomas-Bosco, Pascale Allotey, Therese Curtin, Gitau Mburu, Nancy Santesso, Romina Brignardello-Petersen, Richard Kennedy, Cindy Farquhar, Jacky Boivin, Guido Pennings, Linda C. Giudice, Robert W. Rebar, Luca Gianaroli, Lan N. Vuong, Sandro C. Esteves, Christopher J. De Jonge, Allan Pacey, Willem Ombelet, Tansu Küçük, Barbara Collura, Klaudija Kordic, Paula Amato, Thabo Matsaseng, James Kiarie · 发表于：Human Reproduction · 年份：2025 · DOI：10.1093/humrep/deaf212 · 被引用次数：14 · 研究领域：Reproductive Health and Technologies、Sperm and Testicular Function、Ovarian function and disorders

STUDY QUESTION: What is the recommended prevention, diagnosis, and treatment of infertility among individuals and couples? SUMMARY ANSWER: The World Health Organization (WHO) made 40 recommendations and six good practice statements for the prevention, diagnosis, and treatment of infertility. WHAT IS KNOWN ALREADY: The field of sexual and reproductive health care, including family planning has progressed in the last several decades. Significant progress has also been made in the field of medically assisted reproduction. Globally, one in six people experience infertility in their lifetime. However, many countries do not include the prevention, diagnosis, and treatment of infertility in health policies, financing, and services, and many do not have national clinical guidelines for the prevention, diagnosis, and treatment of infertility. STUDY DESIGN, SIZE, DURATION: The guideline was developed according to the WHO handbook for guideline development. A Guideline Development Group (GDG) was assembled and included a multidisciplinary and regionally diverse set of clinicians, policymakers, researchers, implementers, and representatives of patient groups (n=30). The GDG prioritized key recommendation questions to address in the guideline. PARTICIPANTS/MATERIALS, SETTING, METHODS: New systematic reviews were conducted, or existing reviews updated, to inform the recommendations. The GRADE approach was used to assess the certainty of the evidence and to guide the formulation of recommen...