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Supplementary Figure S6 from Efficacy and Imaging-Enabled Pharmacodynamic Profiling of KRAS G12C Inhibitors in Xenograft and Genetically Engineered Mouse Models of Cancer

作者:Catherine Lee, Ziyue Karen Jiang, Simon Planken, Lisa K. Manzuk, Roberto Ortiz, Michael Hall, Kavon Noorbehesht, Sripad Ram, Timothy Affolter, Gabriel E. Troche, Nathan T. Ihle, Theodore Johnson, Youngwook Ahn, Manfred Kraus, Anand Giddabasappa · 年份:2025 · DOI:10.1158/1535-7163.30733956 · 研究领域:Protein Kinase Regulation and GTPase Signaling、HER2/EGFR in Cancer Research、Melanoma and MAPK Pathways

<p>Individual MLAST curves and biomarker staining from G12C KP animals treated with vehicle, Compound A, and sotorasib</p>