Osteoarthritis year in review 2025: Imaging

作者：Matthew S. Harkey, Anthony A. Gatti, Mylène P. Jansen, McKenzie S. White, Jessica Tolzman, Arjun Parmar, Ian Frederick, Thomas M. Link, Harvi F. Hart · 发表于：Osteoarthritis and Cartilage · 年份：2025 · DOI：10.1016/j.joca.2025.11.004 · 被引用次数：4 · 研究领域：Osteoarthritis Treatment and Mechanisms、Rheumatoid Arthritis Research and Therapies、Bone and Joint Diseases

OBJECTIVE: To conduct a narrative review of selected imaging studies published in the past year, with a focus on how emerging methods and multi-tissue assessments are contributing to disease characterization, early detection, and intervention strategies. DESIGN: We conducted a comprehensive search strategy of PubMed, Embase, and CINAHL for original English-language human studies on imaging in osteoarthritis, published between March 2024 and March 2025. From the 262 full-text studies that met inclusion criteria, we identified a set of representative studies through independent review and group discussion. These studies are organized into five themes that emerged from this study: effusion-synovitis, infrapatellar fat pad, muscle, subchondral bone, and subcutaneous fat. Within each theme, one highlighted study and several additional studies were synthesized, followed by a summary of cross-cutting insights and future directions. RESULTS: A total of 26 studies were included. Collectively, the studies reinforce the importance of viewing osteoarthritis as a condition involving multiple joint structures, with inflammation as a recurring feature across tissues. Muscle quality and local adiposity emerged as consistent imaging biomarkers, while accessible tools such as ultrasound and AI-enhanced radiography demonstrated potential for scalable clinical application. Links between imaging findings and biomechanics, particularly gait and loading patterns, also featured prominently. Cross-cu...