Definition of Sporadic Early-Onset Invasive Solid Organ Cancers in Adults

作者：Savio George Barreto, Irit Ben‐Aharon, Cathy Eng, Shailesh V Shrikhande, Bhawna Sirohi, Kjetil Søreide, Stephen Jacob Pandol · 发表于：Oncology and Therapy · 年份：2025 · DOI：10.1007/s40487-025-00405-8 · 被引用次数：1 · 研究领域：Bladder and Urothelial Cancer Treatments、Cancer Genomics and Diagnostics、Multiple and Secondary Primary Cancers

With a rising incidence globally, there is need to address a basic deficiency, namely, the lack of a clear definition of sporadic early-onset invasive solid organ cancers in adults. This manuscript discusses this need to have a unified understanding of what constitutes sporadic early-onset cancers in adults based on (epi)genetic, biological, and environmental influences with an aim to motivate clinicians and scientists to think about these cancers from a broader perspective when developing their own research programs.