Multifunctional copper-based metal-organic frameworks/chitosan derivative/exosome composite sponge for skin healing

作者：Zhou Heng, Jiaqi Wang, Yulong Ding, Huan Liang, Tao Qin, Pengjiao Wang, Xiuli Gao, Xiaoqing He · 发表于：iScience · 年份：2025 · DOI：10.1016/j.isci.2025.114176 · 被引用次数：2 · 研究领域：Wound Healing and Treatments、Nanoplatforms for cancer theranostics、Pressure Ulcer Prevention and Management

-mediated angiogenesis, and possesses a strong antioxidant capacity. In a rat full-thickness skin-wound model, the sponge suppressed inflammatory cell infiltration, reduced the expression of pro-inflammatory factors, and promoted angiogenesis and collagen deposition, offering an effective therapeutic approach for skin wound healing.