Strengthening chlamydia management in Australian general practice using interventions that align with the clinic workflow: implementation and feasibility trial findings

作者：Jane L. Goller, Z. Alexiou, Helen Bittleston, Meredith Temple‐Smith, Lena Sanci, J. A. Simpson, Marcus Y. Chen, Christopher K Fairley, Deborah Bateson, Christopher Bourne, Natalie Carvalho, Basil Donovan, Stephanie Munari, Jane Tomnay, Rebecca Guy, David G. Regan, David J. Hawkes, Marion Saville, Claudia Estcourt, Jane S. Hocking, Jacqueline Coombe · 发表于：medRxiv · 年份：2025 · DOI：10.1101/2025.11.17.25340442 · 研究领域：Reproductive tract infections research、Adolescent Sexual and Reproductive Health、Syphilis Diagnosis and Treatment

Abstract Objective To evaluate the implementation and impact of the Management of Chlamydia Cases in Australia (MoCCA) intervention for strengthening chlamydia management in Australian general practice. Design Non-randomised implementation and feasibility trial Setting General practices in the Australian states of New South Wales, Queensland and Victoria. Participants 14 general practices participated and implemented the MoCCA intervention. General practitioners (GPs) and nurses from participating clinics were interviewed about implementation and use of MoCCA. Deidentified patient attendance and clinical data for patients aged 16-44 years were collected for each clinic. Intervention Multifaceted intervention (website ( www.mocca.org.au/ ), patient factsheets, shortcuts for documenting a chlamydia consultation, mailed specimen kits for chlamydia retesting, guidance articles, continuing professional development activities) to facilitate chlamydia management in general practice. Clinicians (GPs and nurses) were asked to use the MoCCA intervention to guide their chlamydia and pelvic inflammatory disease (PID) diagnosis and management over a 12-month intervention period. Main outcome measures The primary outcomes focussed on intervention implementation (acceptability, adoption, appropriateness, feasibility, fidelity, penetration, sustainability). Secondary outcomes focused on chlamydia retesting and reinfection among patients who had a chlamydia infection and PID rates among femal...