Photoinduced Multicomponent Sulfonylsulfination of Alkenes via Aromatization-Driven Deconstructive and Radical-Polar Crossover Cyclization Strategies

作者：Wenchao Gao, Yong Teng, Ke‐Xin Huang, Wenguang Li, Wenguang Li, Yongqi Yu, Xu Zhang, Wendian Li, Wendian Li, Ting Li · 发表于：Organic Letters · 年份：2025 · DOI：10.1021/acs.orglett.5c04276 · 被引用次数：6 · 研究领域：Sulfur-Based Synthesis Techniques、Radical Photochemical Reactions、Catalytic C–H Functionalization Methods

A facile methodology, consisting of photoenabled multicomponent coupling of alkenes, spiro-dihydroquinazolinones, and DABSO, is described. This protocol features deconstruction-cyclization efficiency, functional group tolerance, and mild and sustainable conditions, readily producing a series of valuable sulfonylsulfinated derivates with S IV and S VI centers in moderate to high yields. A photoinduced aromatization-mediated deconstructive process and a radical-polar crossover cyclization process involving twofold insertion of SO 2 are proposed in this transformation.