Dyslipidemia in asthma: Treatable trait, or just a common comorbidity?

作者：Ke Deng, Ji Wang, Brian G. Oliver, Lisa G. Wood, Gang Wang · 发表于：Chinese Medical Journal · 年份：2025 · DOI：10.1097/cm9.0000000000003843 · 被引用次数：3 · 研究领域：Asthma and respiratory diseases、Phosphodiesterase function and regulation、Delphi Technique in Research

ABSTRACT: Asthma is a diverse disease that can be categorized into various phenotypes and endotypes, including obesity-re-lated asthma and allergic asthma. "Treatable traits (TTs)" represent a new approach to managing asthma. Asthma accompanied by dyslipidemia would be a distinct asthma phenotype that is becoming increasingly common. Therefore, dyslipidemia can potentially serve as a target for the management of asthma. Nevertheless, it remains highly under-researched compared to other observable traits. Gaining knowledge about the clinical and inflammatory characteristics, underlying mechanisms, and potential therapeutic medications for asthma with dyslipidemia is crucial for its effective management. This review aimed to provide a comprehensive overview of asthma with dyslipidemia, consolidating existing knowledge and ongoing research.