Needle-knife therapy for lumbar disc herniation: A systematic review and meta-analysis

作者：Yiming Zhang, Ruiguo Li, Xiaohong Zhang, Zhanyou Wang, Ziwei Zhang, Huanhuan Xu, Xiaofan Li · 发表于：Medicine · 年份：2025 · DOI：10.1097/md.0000000000045659 · 被引用次数：4 · 研究领域：Spine and Intervertebral Disc Pathology、Surgical Sutures and Adhesives、Cervical and Thoracic Myelopathy

OBJECTIVE: To explore the effectiveness of needle-knife therapy for lumbar disc herniation and its advantages compared with traditional treatments. METHODS: PubMed, Embase, Web of Science, Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, Wanfang Database, China National Knowledge Infrastructure, ClinicalTrials.gov, and the Chinese Clinical Trial Registry were searched with a cutoff date of March 1, 2025. Randomized controlled trial studies comparing needle-knife therapy or needle-knife combined with traditional therapy with traditional therapy were included. Cochrane risk assessment software was used to assess bias risk in the included randomized controlled trials (RCTs). Meta-analysis was conducted using RevMan 5.4.1 software, and GRADE was used to assess the quality of evidence for each outcome. RESULTS: A total of 12 RCTs were included, with 1160 patients. Compared with traditional treatment, needle-knife combined with traditional treatment significantly improved the treatment efficacy (mean difference [MD] = 5.19, 95% confidence interval [CI]: 2.91-9.26, P = .0001, I2 = 0%). Visual Analog Scale (VAS), Japanese Orthopaedic Association (JOA), and Oswestry Disability Index (ODI) scores were all improved compared to traditional treatment (VAS: MD = -1.44, 95% CI: -1.60 to -1.28, P = .0001, I² = 93%, JOA: MD = 2.93, 95% CI: 1.88-3.98, P = .0001, I² = 0%, ODI: MD = -4.93, 95% CI: -5.68 to -4.18, P = .0001, I2 = 0%). Compared with traditio...