Megabase-scale loss of heterozygosity provoked by CRISPR-Cas9 DNA double-strand breaks

作者：Samantha B. Regan, Darpan Medhi, Yuanlin Xu, Travis White, Yi-Zhen Jiang, Jung Eun Kim, Shih-Chun Wang, Qichen Deng, Jia Su, Dulguun Baasan, Jon P. Connelly, Ti-Cheng Chang, Shondra M. Pruett‐Miller, Maria Jasin · 发表于：Molecular Cell · 年份：2025 · DOI：10.1016/j.molcel.2025.10.015 · 被引用次数：15 · 研究领域：CRISPR and Genetic Engineering、RNA regulation and disease、Virus-based gene therapy research