Deep Granuloma Annulare After Scalp Infection: Wolf’s Isotopic Response in a Pediatric Patient

作者：Juliana M O'Reilly, Henok Eskinder, Elaine S. Keung, Luke Bloomquist, Shena Kravitz · 发表于：Cureus · 年份：2025 · DOI：10.7759/cureus.96166 · 研究领域：Skin Diseases and Diabetes、Sarcoidosis and Beryllium Toxicity Research、Autoimmune and Inflammatory Disorders

We present a case of a pediatric patient with recurrent flares of deep granuloma annulare (GA) largely localized to the right scalp and face, corresponding to the area of a previously resolved scalp infection. This clinical pattern is suggestive of Wolf's isotopic response, a phenomenon that has been rarely reported in children. To our knowledge, this may represent one of the first documented cases of deep GA manifesting as Wolf's isotopic response in a pediatric patient.