Female predominance and socio-demographic inequalities in global near vision loss burden: projected trends and disparities from 1990 to 2035

作者：Guodong Tang, Jinghua Li, Xiaoqi Gong, Yu Han, Man Jiang, Yibo Han, Dongfang Wang, Yuxi Liu, Jike Song, Hongsheng Bi · 发表于：Frontiers in Public Health · 年份：2025 · DOI：10.3389/fpubh.2025.1611433 · 被引用次数：1 · 研究领域：Ophthalmology and Visual Impairment Studies、Retinal Diseases and Treatments、Ocular and Laser Science Research

Background: Near vision loss (NVL), a hallmark of aging populations, imposes a growing global health burden, exacerbated by demographic shifts and socioeconomic disparities. Despite its profound impact on productivity and quality of life, comprehensive analyses that integrate aging, socioeconomic development, and sex-specific disparities remain limited. Methods: Using the Global Burden of Disease (GBD) 2021 dataset spanning 204 countries and territories (1990-2021), we evaluated the NVL burden through prevalence, disability-adjusted life years (DALYs), and sociodemographic index (SDI). Advanced methodologies included decomposition analysis to disentangle demographic and epidemiological drivers, Bayesian age-period-cohort (BAPC) modeling for projections, and frontier analysis to quantify SDI-linked inequities. Gender-stratified and age-specific trends were analyzed using joinpoint regression analysis. Results: Global NVL prevalence surged from 428 million to 1.155 billion cases (1990-2021). Females exhibited a higher age-standardized prevalence (16,588 vs. 14,718 per 100,000 in 2021). South Asia had the highest burden (age-standardized DALYs: 208.0), whereas the Gulf Cooperation Council reported the lowest (93.8). Socioeconomic inequities widened: The DALY gap between high- and low-SDI regions expanded from 10.19 to 31.96. Population growth (65.3%) and epidemiological shifts (39.2%) drove DALY increases, offset marginally by aging (-4.4%). Conclusion: NVL burden escalated disp...