Meta-analysis of yoga-based mind-body interventions in the management of inflammatory bowel disease

作者：L. Pan, Xiaotong Chen, Yiqi Wu, Zhanyi Zhou, Donghang Xu · 发表于：Complementary Therapies in Medicine · 年份：2025 · DOI：10.1016/j.ctim.2025.103287 · 被引用次数：2 · 研究领域：Mindfulness and Compassion Interventions、Inflammatory Bowel Disease、Complementary and Alternative Medicine Studies

BACKGROUND: Inflammatory bowel disease (IBD) affects millions worldwide and imposes both physical and psychological burdens. While current treatments have limitations, yoga-based mind-body interventions (YMBIs) show promise in improving symptoms and quality of life through physiological and stress-regulating pathways. OBJECTIVE: This Meta-analysis seeks to comprehensively and objectively assess the efficacy of yoga-based mind-body interventions on psychological, physical, and inflammatory outcomes in patients with IBD. METHODS: A comprehensive search was conducted in both international and Chinese databases including PubMed, EMBASE, Cochrane Library, Web of Science, Medline, China National Knowledge Infrastructure (CNKI), WanFang, and China Biomedical Literature Service System. Randomized controlled trials (RCTs) comparing YMBIs with standard care or placebo in IBD patients were pooled from inception to February 17, 2025. Data were analyzed using RevMan 5.4 and Stata 16.0, with standardized mean differences (SMDs) and 95 % confidence intervals (CIs) as effect measures. RESULTS: Seven RCTs comprising 502 participants were included. The meta-analysis revealed that YMBIs significantly reduced anxiety (SMD = -0.56, 95 % CI [-0.77 to -0.36], P < 0.0001), depression (SMD = -3.45, 95 % CI [-5.52 to -1.37], P < 0.0001), and perceived stress (SMD = -0.70, 95 % CI [-1.00 to -0.39], P < 0.0001), while improving quality of life (SMD = 0.47, 95 % CI [0.17-0.77], P = 0.002). Effects on sle...