Effectiveness of nurse-led mHealth interventions on symptom outcomes in adult patients with cancer: a systematic review and meta-analysis

作者：Chenxing Zhang, Yuezhen Hong, Yu‐Jia Chen, Rachel Arbing, Wei‐Ti Chen, Feifei Huang · 发表于：BMC Nursing · 年份：2025 · DOI：10.1186/s12912-025-03981-2 · 被引用次数：7 · 研究领域：Cancer survivorship and care、Childhood Cancer Survivors' Quality of Life、Mobile Health and mHealth Applications

BACKGROUND: Patients with cancer face a high symptom burden, but traditional care models often lack timely, personalized support during home recovery. Nurse-led mobile health (mHealth) interventions show promise in bridging this gap. However, evidence on their effectiveness and reporting quality remains limited. This study evaluated the impact of nurse-led mHealth interventions on symptom outcomes in adult patients with cancer and assessed reporting completeness using the WHO mERA framework. METHODS: A systematic search of 10 electronic databases included studies published before January 27, 2025. Eligible studies were randomized controlled trials (RCTs) evaluating nurse-led mHealth interventions for cancer symptom outcomes. The risk of bias was assessed via the Cochrane Risk of Bias 2.0 tool. The meta-analyses were conducted via random-effects models, with effect sizes expressed as standardized mean differences (SMDs) with 95% confidence intervals (CIs). Sensitivity analyses explored sources of heterogeneity. Intervention characteristics were categorized using the Omaha System, and reporting quality was evaluated with the mHealth Evidence Reporting and Assessment (mERA) checklist. RESULTS: A total of 14 RCTs involving 1,972 participants were included. Pooled results from high-certainty evidence revealed that nurse-led mHealth interventions significantly improved depression (SMD = − 0.42, 95% CI [− 0.57, − 0.27], p < 0.001). There was low-certainty evidence suggesting potenti...