CRISPR/Cas9 library screening uncovered CCT2 as a critical driver of acquired resistance to EGFR-targeted therapy by stabilizing TMX1 in non-small cell lung cancer

作者：Zihao Ke, Qi Zhang, Xingyu Chen, Rongrong Jin, Gaohua Han, Qianhua Cao, Ke Zhu, Shihui Wei, Jiajin Chen, Qian Wang, Meiling Zhang, Weina Huang, Kaimin Li, Kunlong Xiong, Kaihua Lu, Ying Chen, Chao Cao · 发表于：Cell Death and Differentiation · 年份：2025 · DOI：10.1038/s41418-025-01600-w · 被引用次数：1 · 研究领域：Lung Cancer Treatments and Mutations、interferon and immune responses、CRISPR and Genetic Engineering