Burden of cardiovascular diseases in England (2020–24): a national cohort using electronic health records data

作者：Elias Allara, Wenzhong Shi, Thomas Bolton, Fionna Chalmers, Luigi Filippo Brizzi, Liam Musto, Anoop Shah, Christopher Tomlinson, Isabel Walter, Nathalie Conrad, John Danesh, Emanuele Di Angelantonio, Steffen E Petersen, Kamlesh Khunti, Elena Raffetti, Geneviève Cézard, Spiros Denaxas, Angela Wood, William Whiteley · 发表于：The Lancet Public Health · 年份：2025 · DOI：10.1016/s2468-2667(25)00163-x · 被引用次数：7 · 研究领域：COVID-19 and healthcare impacts、COVID-19 Clinical Research Studies、Health Promotion and Cardiovascular Prevention

BACKGROUND: The COVID-19 pandemic led to substantial health services disruption in England. Health-care policy makers need reliable national-level information on disease burden to plan services. Whole-population individual-level data, which are routinely collected and linked across multiple sources, provide comprehensive estimates that can be regularly updated at low cost. We aimed to measure the burden of cardiovascular diseases in the whole population of England from 2020 to 2024. METHODS: Using linked National Health Service England hospital, primary care, death, and specialist registers between Jan 1, 2020, and May 31, 2024, we defined 79 common and rare cardiovascular diseases, and estimated incidence, prevalence, 30-day case fatality, and post-diagnosis rates of myocardial infarction and ischaemic stroke, focusing on five common conditions (myocardial infarction, ischaemic stroke, heart failure, atrial fibrillation, and peripheral vascular disease), as well as pulmonary embolism, myocarditis, and intracranial venous thrombosis. We conducted subgroup analyses based on and adjusted for age, sex, ethnicity, long-term conditions, deprivation, and geographical area. FINDINGS: Analysis of data for 57 406 990 people in England between 2020 and 2024 revealed changes in cardiovascular disease burden. Although incidences after the pandemic were generally stable for the five common diagnoses, myocardial infarction (events per 100 000 person-years: 245·2 vs 216·9; -12%, 95% CI -17 ...