Supplementary Figure 11 from Mapping the Proteomic Landscape of Pancreatic Cancer: Prognostic Insights and Subtype Stratification

作者：Adel T. Aref, Jason Grealey, Mohashin Pathan, Zainab Noor, Asim Anees, AKM Azad, Daniela Lee Smith, Erin M. Humphries, Daniel Bucio-Noble, Jennifer M.S. Koh, Erin K. Sykes, Steven G. Williams, Ruth J. Lyons, Natasha Lucas, Dylan Xavier, Sumit Sahni, Anubhav Mittal, Jaswinder S. Samra, John V. Pearson, Nicola Waddell, Olga Kondrashova, Angela Chou, Loretta Sioson, Amy Sheen, Venkateswar Addala, Lesley Andrews, Jennifer Arena, Ray Asghari, Mo Ballal, Andrew P. Barbour, Claudio Bassi, Maria Beilin, Andrew V. Biankin, Nicola Blackburn, Mark E. Brooke‐Smith, Diego Chacon Fajardo, Cecilia R. Chambers, David K. Chang, Lorraine A. Chantrill, John Chen, Angela Chou, Andrew D. Clouston, Vincenzo Corbo, Peter H. Cosman, Thomas R. Cox, Amitabha Das, Stephan B. Dreyer, Tanya Dwarte, Krishna Epari, James R. Eshleman, Jonathan W. Fawcett, Kynan Feeney, David Fletcher, Cindy Forrest, Anthony J. Gill, Annabel Goodwin, Peter Grimison, Sean M. Grimmond, Michael Hatzifotis, David Herrmann, Hilda A. High, Peter Hodgkinson, Oliver Hofmann, Oliver Holmes, Ralph H. Hruban, Kasim Ismail, Nigel B. Jamieson, Gloria Jeong, Amber L. Johns, James G. Kench, Judy Kirk, Rita T. Lawlor, Conrad Leonard, Ruth J. Lyons, Duncan McLeod, R. Scott Mead, Neil D. Merrett, Anubhav Mittal, Sanjay Mukhedkar, Adnan Nagrial, Felicity Newell, Nan Q. Nguyen, Mehrdad Nikfarjam, Max Nobis, Kátia Nones, Thomas J. O’Rourke, Marina Pajic, Virginia Papangelis, Nick Pavlakis, John V. Pearson, Brooke Pereira, Sean Porazinski, Daniel A. Reed, Shona Ritchie, Alice Russo, Andrew Ruszkiewicz, Jaswinder S. Samra, Charbel Sandroussi, Aldo Scarpa, Kellee Slater, Allan Spigellman, Alina Stoita, Michael Texler, Paul Timpson, Katherine L. Tucker, Claire Vennin, Nicola Waddell, David Williams, Christopher L. Wolfgang, Scott J. Wood, Chris Worthley, Nikolajs Zeps, Peter G. Hains, Phillip J. Robinson, Qing Zhong, Roger R. Reddel, Anthony J. Gill · 年份：2025 · DOI：10.1158/2767-9764.30432968 · 研究领域：Pancreatic and Hepatic Oncology Research、Cancer Genomics and Diagnostics、Ferroptosis and cancer prognosis

<p>Supplementary Figure 11 shows the differential abundance and pathway enrichment analyses based on the KRAS-G12C status. (A) Volcano plot displaying the differentially abundant proteins between tumors harboring the KRAS-G12C mutation versus any other KRAS-G12 mutation. (B) Pathways enriched in the KEGG, Reactome, and WikiPathways databases based on the upregulated proteins from tumors that harbored KRAS-G12C mutations when compared to tumors with other KRAS12 mutations.</p>