Evaluating Weight Gain in Infants Treated With Presurgical Lip, Alveolus, and Nose Approximation (PLANA): A Pilot Study

作者：Lucas R. Perez Rivera, Melanie Rosa-Chaves, Neha Amitoz Multani, Natalie M. Plana, Deborah Malkoff-Cohen, David Alan Staffenberg, Roberto L. Flores, Pradip R. Shetye, Margaret M. Lico · 发表于：Journal of Craniofacial Surgery · 年份：2025 · DOI：10.1097/scs.0000000000012100 · 被引用次数：6 · 研究领域：Cleft Lip and Palate Research、Craniofacial Disorders and Treatments、Tracheal and airway disorders

Presurgical lip, alveolus, and nose approximation (PLANA) is a novel form of presurgical infant orthopedics (PSIO) designed without an intraoral molding plate. While early studies on PLANA have demonstrated improvements in nasolabial morphology, its impact on infant feeding and weight gain has not been assessed. A single-institution, retrospective review of all patients with cleft lip and palate (CL±P) treated with PLANA over a 1-year period was therefore performed. Weight values at baseline and at surgery were compared with World Health Organization (WHO) Child Growth Standards, and weight-for-age z-scores (WAZ) as well as changes in weight-for-age z-scores (WAZ) were obtained. A cohort of patients who underwent PSIO with NasoAlveolar Molding (NAM) was evaluated as a reference group. The PLANA (n=19) and NAM (n=25) groups were comparable in age (15.63 versus 21.16 d, P=0.2), weight (3.38 versus 3.50 kg, P=0.2), and WAZ (-0.80 versus -0.94, P=0.8) at baseline, and in age (103.11 versus 113.04 d, P=0.06), weight (5.82 versus 5.68 kg, P=0.3), and WAZ (-0.92 versus -1.47, P=0.2) at surgery. Both groups had similar weight gain (2.44 versus 2.18 kg, P=0.1) and WAZ (-0.12 versus -0.53, P=0.2). The PLANA group exhibited statistically significant greater daily weight gain (0.028 versus 0.024 kg/d, P=0.04). None of the patients experienced surgical delays due to insufficient weight gain. PLANA did not interfere with presurgical weight gain in infants with CL±P.